BRAIN Initiative Viral Vector Core
Custom Viral Vectors for Neuroscience
Offering AAV, Rabies, Lenti, and HSV
Get vector design, production, and performance optimization tailored for your work.
“The service, product quality, speed and price of UNC NeuroTools are unmatched”
“The people in NeuroTools Viral Vector Core are always working hard to accommodate our requests. So our lab members and I really appreciate their high-quality work.”
“Very happy with the product that we received. It has worked really well for us. I was especially grateful that Kim provided us with some additional buffer so that we could dilute all of our viruses to the same titer prior to aliquoting, freezing, and storing.”
Featured Collections
-
"My laboratory develops, disseminates, and uses multi-color, genetically encoded indicators that sense released neurotransmitters, neuromodulators, and neuropeptides. We aim to understand the complex interactions of released neurochemicals on neural activity. Using a novel high-throughput sensor engineering platform, including ligand-binding scaffolds, computational modeling, and machine learning-guided directed evolution, we create highly optimized sensors covering the full-color spectrum with enhanced chemical specificity, resolution, and depth across biological systems."
-
"HSV possesses multiple features that make it an ideal vector for delivery of genes into the nervous system. In particular, it accepts large molecules of exogenous DNA; it infects non- dividing cells from a wide range of hosts with high efficiency; it enables strong expression of foreign genes; it is episomal, and thereby does not cause integration effects; its infection of postmitotic cells is persistent; and HSV-1 particles can be concentrated to relatively high titers. Be- cause of these characteristics of HSV-1, and because it is neurotropic, it is currently one of the best viral vectors available for functional analysis of genes in the nervous system." (Neve & Carlezon, Jr. 2002)
Learn more: https://acnp.org/wp-content/uploads/2017/11/CH20_253-262.pdf
Want to Place an Order?
-
Register for a NeuroTools Account
Register with our ordering platform to streamline your requests. Create a unique username and password.
-
Place an Order
Login to your account to place an order. Receive updates and provide feedback.